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 超高压能够对非共价键(氢键、离子键、疏水键)产生影响,而共价键影响并不敏感,故生物大分子成分可发生变性,而对小分子物质(如皂苷、黄酮、生物碱、挥发油、单糖、维生素、色素等)的分子结构没有影响[11]。因此,高压具有可使蛋白质变性、酶失活、微生物死亡,而不破坏药物中的小分子有效成分的生理活性,可以达到提取、灭菌的目的。超高压技术与其他传统的提取技术相比,具有许多独特的优势,具体表现在以下方面?</p> <p style="text-align:center;"> <img src="/uploads/image/20190801/20190801092202_2968.jpg" alt="" /> </p> 1  提取时间?br />       <b>超高压提?/b>的升压和保压阶段中,超高的压力差使提取溶剂迅速渗透到固体药物组织内部,有效成分快速溶解在提取溶剂中;卸压阶段中,超高的反向压力差为溶解在提取溶剂中的有效成分,由固体组织内部向外的扩散提供了超高的传质动力,有效成分能够快速扩散到固体组织外,因此超高压技术能显著地缩短提取时间?br /> 2  溶剂消耗少<br />       超高压提取是在一个完全封闭的条件下进行的,没有溶剂的挥发消耗,而且目标成分由固体组织向周围溶剂的扩散,不是单纯靠浓度梯度提供传质动力,而是主要靠压力差提供。因此,超高压技术选择的固体原料与提取溶剂的比例较其他方法都要少,能明显地降低溶剂的消耗?br /> 3  提取效率高、得率高<br />       超高压提取的压力最高可?00 MPa。在这样高的压力下,可以显著地提高提取效率,并且在超高压下,组织结构发生变化,与溶剂的接触面积增大,传质阻力降低,有效成分溶解迅速、充分,因而提取得率高?br /> 4  提取温度?br />       在绝热条件下,压力每提高100 MPa,水的温度升? ℃左右。实际提取时,由于高压容器壁与周围环境有热交换,温度升高的程度远小于上述数值。因此,高压提取可以维持在接近常温的条件下进行。这对于天然产物中的热敏性成分以及易挥发性成分的提取是极为有利的。同时,由于超高压提取使用的是流体静压力,压力传递是在瞬间完成的,容器内任何方向和位置的压力相等,因此超高压提取对物料的作用是均匀一致的。这就避免了像微波提取、热回流提取过程中因局部受热不均,造成目标成分的结构变化和损失,从而保证了有效成分具有更高的生物活性?br /></p> </div> <div id="66ov23rl" class="newArtiNext mt10"><div>上一?<a href="177.html">超高压杀菌设备有什么优?/a></div> <div>下一?<a href="175.html">食用菌灭菌设备减少食用菌菌种受污?/a></div> </div> <div id="66ov23rl" class="tag">相关标签?/div> <div id="66ov23rl" class="crumb mt20"> <span class="fl font_w fb fs22">相关新闻<span class="fs14 fn font_i ml5">RELATED NEWS</span></span> </div> <div id="66ov23rl" class="insNews clearfix pt10 fs14 font_w"> <ul> <li><a href="/news/203.html" rel="nofollow">新型食用菌灭菌设备功能有什?/a><span>2020-06-24</span></li> <li><a href="/news/202.html" rel="nofollow">食品超高压灭菌的作用有什?/a><span>2020-06-10</span></li> <li><a href="/news/201.html" rel="nofollow">超高压设备特性有什?/a><span>2020-05-27</span></li> <li><a href="/news/200.html" rel="nofollow">超高压技术的发展</a><span>2020-05-13</span></li> 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